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Written on July 16th, 2018 by Maarten Coonen

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FAIR data management and DISQOVERability

I recently spoke at the iRODS User Group Meeting 2018 (June 5-7 2018, Durham, NC, USA) on the FAIR principles and how our research community is using the semantic platform DISQOVER in our DataHub infrastructure. Here’s the story from that session explaining how we link on-premise clinical data with other sources to gain more, better and faster insights.

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Written on March 6th, 2018 by Bérénice Wulbrecht

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Explore Genetic Variation of Human Cancer Genes in DISQOVER

One of the key types of information in DISQOVER is human genetic variations and their links to genes, diseases etc. We recently integrated two new data sources: 1000 Genomes and gnomAD. These data sources include human variation and genotype data derived from a large set of human individuals.

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Written on March 6th, 2018 by Bérénice Wulbrecht

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Search for Adverse Events in DISQOVER

DISQOVER is now also hosting a new canonical type: Adverse Event. It contains reports of untoward medical occurrences and treatments, without necessary causal relationship.

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Written on August 30th, 2017 by Filip Pattyn

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Bringing down the virtual walls around hospital data

Integrating an organization’s internal data is challenging. It requires strategic vision by the organization’s leadership and an open mindset on different levels. In our experience, establishing such a solution has a greater chance of success if stakeholders quickly and easily notice the benefits. Small pragmatic initiatives with few data sources that solve a limited number of use-cases, can demonstrate how things can improve for the whole organization.

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Written on July 6th, 2017 by Filip Pattyn

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Connected Data landscapes: a Self-Service Knowledge Platform at Amgen

One and a half years ago we started to work with Amgen to help them improve the way they search and retrieve research data. They were looking for a solution that could aggregate and interlink their internal research data, enrich it with public data and provide an appealing, user-friendly interface for end-users.

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Written on June 9th, 2017 by Bérénice Wulbrecht

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ONTOFORCE at the Bio-IT World 2017 FAIR Hackathon

In May 2017, Bio-IT World hosted its first hackathon on FAIR data. As ONTOFORCE, we helped organize the event and devoted a team to the competition on ‘Aligning a dataset to FAIR principles’. Here’s our report.

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Written on May 23rd, 2017 by Hans Constandt

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Why data should be FAIR

FAIR is a fairly recent concept that stands for ‛Findable, Accessible, Interoperable and Reusable’. On the face of it, these principles don’t seem so remarkable. But what sets it apart, compared to other (earlier) open data models, is that the emphasis has shifted from the human researcher to machines.

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Written on January 24th, 2017 by Filip Pattyn

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Bring epidemiology data and disease genes in closer contact

In my previous blog, I tried to explain that the usage of different disease classifications or encodings in data sources like the US and EU clinical trial registries, doesn’t hamper the integration and linking of this kind of data.

Disease classifications are also used to precisely define diseases in other contexts like epidemiology, pharmacovigilance, toxicology, pharmacology, genetics, etc. This data is scattered across a plethora of data sources, maintained by different governmental and other non-profit organizations like research consortia and institutes or individual research groups. If they are keen on providing meaningful and useful data, data providers try to avoid using disease terms that aren’t defined precisely in an ontology.

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Written on December 6th, 2016 by Filip Pattyn

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It only takes 3 days (to integrate your data)

Anyone who’s ever been involved in data integration will confirm: integration projects are usually cumbersome and very time- and resource-intensive. Those facts alone take the wind out of the sails of many a company. Most, in fact, don’t even begin data integration projects.
But it doesn’t have to be like that. Integrating your first datasets into our semantic platform DISQOVER, happens in just 3 days. There’s no need for long trajectories! Within 3 days, your first internal datasets are searchable and you’re even trained to add additional datasets yourself.
Here’s how it works.

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Written on April 5th, 2016 by Filip Pattyn

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The gap shouldn’t be that wide between US and EU clinical trials

Human beings, and to a greater extent scientists, try to order items for a purpose. In biomedical sciences, probably no other subject is more diversely ordered or classified as human conditions or diseases – hereinafter abbreviated as ‘diseases’. None of these classifications claims to be the one and only truth or is able to serve all purposes. Instead, many classifications co-exist and are widely accepted – or enforced – by the various stakeholders in life sciences: lab scientists, clinicians, pharmaceutical and biotech firms, regulatory bodies, governments, etc. With different classifications come different definitions of terms even if they are highly similar or have exactly the same meaning.

But what about searching, comparing and analyzing similar data where different diseases classifications are applied? Or what about compiling data about diseases that are produced and maintained for a specific purpose?

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